HitPredict

Interactor 1: ATG7 (O95352)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)
Gene: ATG7

Interactor 2: ATG10 (Q9H0Y0)
Ubiquitin-like-conjugating enzyme ATG10 (EC 2.3.2.-) (Autophagy-related protein 10) (APG10-like)
Gene: ATG10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.903

The method score is based on:

Property	Details
Experiments	26186194, 28514442, 33961781, 20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	ATG7_N~Autophagy_act_C, Autophagy_act_C~ThiF
Common GO terms	GO:0000045 - autophagosome assembly GO:0005829 - cytosol GO:0006497 - protein lipidation GO:0006914 - autophagy GO:0015031 - protein transport and 3 others more... GO:0016236 - macroautophagy GO:0031401 - positive regulation of protein modification process GO:0032446 - protein modification by small protein conjugation
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1	703
Hs

1	220

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024