HitPredict

Interactor 1: ATG7 (O95352)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)
Gene: ATG7

Interactor 2: MLP3A (Q9H492)
Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A) (Autophagy-related ubiquitin-like modifier LC3 A) (MAP1 light chain 3-like protein 1) (MAP1A/MAP1B light chain 3 A) (MAP1A/MAP1B LC3 A) (Microtubule-associated protein 1 light chain 3 alpha)
Gene: MAP1LC3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.961

The method score is based on:

Property Details
Experiments 16303767, 36576150, 29033323, 25601754, 31857589, 20562859, 11096062
Identification Methods pull down, enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATG8~ThiF
Common GO terms GO:0000045 - autophagosome assembly
GO:0005829 - cytosol
GO:0006995 - cellular response to nitrogen starvation
GO:0009267 - cellular response to starvation
GO:0016236 - macroautophagy
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 703
Hs

1 121
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+ At
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+ Ce
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+ Sc
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024