Interactor 1: ATG7 (O95352)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)
Gene: ATG7

Interactor 2: ATG3 (Q9NT62)
Ubiquitin-like-conjugating enzyme ATG3 (EC 2.3.2.-) (Autophagy-related protein 3) (APG3-like) (hApg3) (Protein PC3-96)
Gene: ATG3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 28514442, 11825910, 33961781, 20562859, 26043688, 24186333
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATG7_N~Autophagy_act_C, Autophagy_act_C~ThiF
Common GO terms GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0015031 - protein transport
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 703
Hs

1 314
+ Mm
+ At
+ Hs
+ Mm
+ Ce
+ Sc
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024