HitPredict

Interactor 1: ATG7 (O95352)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)
Gene: ATG7

Interactor 2: HERC5 (Q9UII4)
E3 ISG15--protein ligase HERC5 (EC 2.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5)
Gene: HERC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35671810
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051607 - defense response to virus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 703 Hs			1 1024
+	Hs
		1354311 SAE2_HUMAN (343-550): 1.16e-55: 203: 20.67		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		313159 MOCS3_HUMAN (331-536): 4.94e-51: 186: 20.48		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		1252665 UBA3_HUMAN (353-550): 9.31e-51: 185: 18.87		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		607185 UBA1_HUMAN (329-478): 1.38e-28: 124: 17.33		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		48142 UBA6_HUMAN (318-528): 3.78e-21: 101: 13.83		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		983261 SAE2_HUMAN (343-550): 1.16e-55: 203: 20.67		UBE3A_HUMAN (414-1024): 1.12e-172: 529: 25.37
+	Hs
		125155 UBA1_HUMAN (329-478): 1.38e-28: 124: 17.33		WWP2_HUMAN (599-1024): 1.14e-167: 516: 22.02
+	Hs
		607135 UBA1_HUMAN (329-478): 1.38e-28: 124: 17.33		ITCH_HUMAN (593-1024): 1.76e-165: 511: 24.22
+	Hs
		48079 UBA6_HUMAN (318-528): 3.78e-21: 101: 13.83		WWP2_HUMAN (599-1024): 1.14e-167: 516: 22.02
+	Hs
		48128 UBA6_HUMAN (318-528): 3.78e-21: 101: 13.83		ITCH_HUMAN (593-1024): 1.76e-165: 511: 24.22
+	Hs
		313135 MOCS3_HUMAN (331-536): 4.94e-51: 186: 20.48		HERC4_HUMAN (317-431): 2.55e-13: 76.6: 11.02