HitPredict - High confidence protein-protein interactions

Interactor 1: ZBT7A (O95365)
Zinc finger and BTB domain-containing protein 7A (Factor binding IST protein 1) (FBI-1) (Factor that binds to inducer of short transcripts protein 1) (HIV-1 1st-binding protein 1) (Leukemia/lymphoma-related factor) (POZ and Krueppel erythroid myeloid ontogenic factor) (POK erythroid myeloid ontogenic factor) (Pokemon) (Pokemon 1) (TTF-I-interacting peptide 21) (TIP21) (Zinc finger protein 857A)
Gene: ZBTB7A

Interactor 2: ZBT7A (O95365)
Zinc finger and BTB domain-containing protein 7A (Factor binding IST protein 1) (FBI-1) (Factor that binds to inducer of short transcripts protein 1) (HIV-1 1st-binding protein 1) (Leukemia/lymphoma-related factor) (POZ and Krueppel erythroid myeloid ontogenic factor) (POK erythroid myeloid ontogenic factor) (Pokemon) (Pokemon 1) (TTF-I-interacting peptide 21) (TIP21) (Zinc finger protein 857A)
Gene: ZBTB7A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.857

Property	Details
Experiments	21804610, 9973611, 17189472
Identification Methods	fluorescent resonance energy transfer, pull down, affinity chromatography technology, x-ray crystallography
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	BTB~BTB, zf-C2H2~zf-C2H2
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000381 - regulation of alternative mRNA splicing, via spliceosome GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001222 - transcription corepressor binding and 31 others more... GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0003677 - DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006110 - regulation of glycolytic process GO:0006325 - chromatin organization GO:0006338 - chromatin remodeling GO:0006351 - DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0030183 - B cell differentiation GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway GO:0034504 - protein localization to nucleus GO:0035035 - histone acetyltransferase binding GO:0035861 - site of double-strand break GO:0042981 - regulation of apoptotic process GO:0043249 - erythrocyte maturation GO:0045444 - fat cell differentiation GO:0045746 - negative regulation of Notch signaling pathway GO:0045892 - negative regulation of DNA-templated transcription GO:0046332 - SMAD binding GO:0046872 - metal ion binding GO:0050681 - nuclear androgen receptor binding GO:0051090 - regulation of DNA-binding transcription factor activity GO:0051092 - positive regulation of NF-kappaB transcription factor activity GO:0060766 - negative regulation of androgen receptor signaling pathway GO:0070418 - DNA-dependent protein kinase complex GO:0097680 - double-strand break repair via classical nonhomologous end joining GO:0140297 - DNA-binding transcription factor binding GO:1990837 - sequence-specific double-stranded DNA binding GO:2000677 - regulation of transcription regulatory region DNA binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1	584
Hs

1	584

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Last updated: 15 Jul 2024