HitPredict

Interactor 1: ZBT7A (O95365)
Zinc finger and BTB domain-containing protein 7A (Factor binding IST protein 1) (FBI-1) (Factor that binds to inducer of short transcripts protein 1) (HIV-1 1st-binding protein 1) (Leukemia/lymphoma-related factor) (POZ and Krueppel erythroid myeloid ontogenic factor) (POK erythroid myeloid ontogenic factor) (Pokemon) (Pokemon 1) (TTF-I-interacting peptide 21) (TIP21) (Zinc finger protein 857A)
Gene: ZBTB7A

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 584 Hs			1 768
+	Hs
		73009 ZN879_HUMAN (60-561): 1.11e-142: 426: 13.59		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041826 Z585A_HUMAN (97-583): 1.11e-133: 409: 12.94		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042371 ZN184_HUMAN (80-581): 8.41e-132: 404: 12.95		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042724 ZN624_HUMAN (97-583): 1.72e-128: 399: 12.16		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		846676 ZNF84_HUMAN (97-583): 1.47e-129: 398: 13.37		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		983757 ZNF91_HUMAN (88-581): 6.17e-115: 370: 15.06		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042045 ZN615_HUMAN (115-488): 1.07e-104: 333: 16.15		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041657 ZKSC8_HUMAN (323-574): 1e-99: 315: 25.98		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042050 ZN565_HUMAN (117-562): 6.47e-98: 310: 15.93		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042053 ZN527_HUMAN (159-535): 1.93e-79: 263: 16.11		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042288 HIC2_HUMAN (2-489): 8.35e-79: 262: 20.90		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042576 PATZ1_HUMAN (12-499): 1.18e-76: 258: 24.09		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041998 ZN100_HUMAN (272-527): 2.5e-76: 253: 22.48		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042051 ZN383_HUMAN (120-491): 3.61e-77: 253: 16.62		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		565092 ZNF7_HUMAN (357-582): 1.41e-69: 239: 20.72		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042336 ZN300_HUMAN (364-574): 2.73e-67: 231: 24.65		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		196609 ZBT24_HUMAN (222-571): 2.69e-64: 225: 17.96		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1043181 ZBT18_HUMAN (11-495): 2.19e-94: 300: 23.72		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043160 HIC2_HUMAN (2-489): 8.35e-79: 262: 20.90		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1041071 ZBT46_HUMAN (9-471): 8.99e-83: 271: 22.87		CUL1_HUMAN (18-768): 0: 707: 30.57