HitPredict

Interactor 1: IPO7 (O95373)
Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7)
Gene: IPO7

Interactor 2: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36244648, 37045861
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1038 Hs			1 648
+	Hs
		312167 IPO7_HUMAN (1-1038): 0: 902: 100.00		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		178095 IPO8_HUMAN (1-1032): 0: 822: 64.41		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		373940 XPO2_HUMAN (2-921): 1.6e-168: 521: 17.50		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374714 IPO9_HUMAN (4-996): 5e-121: 398: 15.05		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374247 IMB1_HUMAN (5-785): 2.49e-114: 375: 12.82		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		488781 IPO9_HUMAN (4-996): 5e-121: 398: 15.05		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Dm
		507747 IPO9_DROME (4-983): 5.63e-116: 383: 14.86		KRAF1_DROME (45-647): 6.35e-165: 491: 44.98
+	Hs
		488718 IMB1_HUMAN (5-785): 2.49e-114: 375: 12.82		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28