HitPredict

Interactor 1: IPO7 (O95373)
Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7)
Gene: IPO7

Interactor 2: KS6A2 (Q15349)
Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)
Gene: RPS6KA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	31678930, 32707033
Identification Methods	proximity labelling technology, affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1038 Hs			1 733
+	Hs
		178169 IPO8_HUMAN (1-1032): 0: 822: 64.41		KS6A2_HUMAN (1-733): 0: 824: 100.00
+	Dm
		1358798 Q9VSD6_DROME (1-1032): 0: 774: 52.79		JIL1_DROME (16-720): 0: 572: 32.21
+	Hs
		312411 IPO7_HUMAN (1-1038): 0: 902: 100.00		KS6B2_HUMAN (415-726): 8.17e-118: 364: 27.88
+	Hs
		1071682 IPO9_HUMAN (4-996): 5e-121: 398: 15.05		KS6A2_HUMAN (1-733): 0: 824: 100.00
+	Dm
		1366297 IPO9_DROME (4-983): 5.63e-116: 383: 14.86		Q9VR61_DROME (20-727): 0: 716: 53.67
+	Dm
		1358789 Q9VN44_DROME (4-956): 3.2e-115: 383: 13.44		JIL1_DROME (16-720): 0: 572: 32.21
+	Hs
		568602 XPO2_HUMAN (2-921): 1.6e-168: 521: 17.50		KAPCA_HUMAN (402-707): 8.01e-119: 362: 29.78
+	Dm
		1213396 IPO9_DROME (4-983): 5.63e-116: 383: 14.86		AKT1_DROME (413-715): 1.79e-124: 386: 26.90
+	Hs
		127393 IPO5_HUMAN (4-955): 1.57e-121: 400: 11.44		KS6B2_HUMAN (415-726): 8.17e-118: 364: 27.88
+	Hs
		127177 IPO5_HUMAN (4-955): 1.57e-121: 400: 11.44		KAPCA_HUMAN (402-707): 8.01e-119: 362: 29.78
+	Dm
		1276808 IPO9_DROME (4-983): 5.63e-116: 383: 14.86		Q94533_DROME (412-713): 1.3e-96: 309: 26.25