Interactor 1: SLU7 (O95391)
Pre-mRNA-splicing factor SLU7 (hSlu7)
Gene: SLU7

Interactor 2: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.740

The method score is based on:

Property Details
Experiments 22365833
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PRO8NT~Slu7, PRP8_domainIV~Slu7, Slu7~U6-snRNA_bdg
Common GO terms GO:0000375 - RNA splicing, via transesterification reactions
GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008380 - RNA splicing
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 586
Hs

1 2335
+ Sc

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Last updated: 15 Jul 2024