HitPredict

Interactor 1: A0A0S2Z4D7 (A0A0S2Z4D7)
NCK adaptor protein 1 isoform 2 (NCK adaptor protein 1, isoform CRA_b)
Gene: NCK1

Interactor 2: WASL (O00401)
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)
Gene: WASL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	26871637
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 170 Hs			1 505
+	Hs
		203198 LCK_HUMAN (3-169): 3.75e-50: 169: 19.43		SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85
+	Hs
		166024 FYN_HUMAN (6-160): 4.63e-46: 159: 20.73		SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85
+	Mm
		435880 HCK_MOUSE (2-169): 7.21e-52: 174: 21.59		WASP_MOUSE (16-487): 4.45e-46: 170: 39.21
+	Mm
		411923 LCK_MOUSE (3-169): 2.41e-49: 167: 19.43		WASP_MOUSE (16-487): 4.45e-46: 170: 39.21
+	Mm
		763384 FYN_MOUSE (6-160): 4.58e-46: 159: 20.73		WASP_MOUSE (16-487): 4.45e-46: 170: 39.21
+	Hs
		442791 HCK_HUMAN (2-169): 1.03e-52: 176: 21.59		WASP_HUMAN (16-313): 7.4e-38: 147: 44.41
+	Mm
		403427 SRC_MOUSE (6-166): 2.06e-43: 152: 18.82		WASP_MOUSE (16-487): 4.45e-46: 170: 39.21
+	Hs
		411631 LCK_HUMAN (3-169): 3.75e-50: 169: 19.43		WASP_HUMAN (16-313): 7.4e-38: 147: 44.41
+	Hs
		454805 FGR_HUMAN (6-166): 2.81e-47: 162: 19.41		WASP_HUMAN (16-313): 7.4e-38: 147: 44.41
+	Hs
		412072 FYN_HUMAN (6-160): 4.63e-46: 159: 20.73		WASP_HUMAN (16-313): 7.4e-38: 147: 44.41
+	Hs
		297808 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		K0754_HUMAN (143-499): 5.78e-32: 132: 13.08
+	Hs
		126898 LCK_HUMAN (3-169): 3.75e-50: 169: 19.43		WASL_HUMAN (378-485): 2.86e-29: 122: 100.00
+	Hs
		126905 SRC_HUMAN (6-166): 2.04e-43: 152: 18.82		WASL_HUMAN (378-485): 2.86e-29: 122: 100.00
+	Hs
		412411 FYN_HUMAN (6-160): 4.63e-46: 159: 20.73		DYN3_HUMAN (281-367): 4.37e-18: 89.6: 29.79
+	Hs
		433891 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		MINK1_HUMAN (269-432): 1.39e-11: 69.2: 22.16
+	Hs
		411790 LCK_HUMAN (3-169): 3.75e-50: 169: 19.43		MINK1_HUMAN (269-432): 1.39e-11: 69.2: 22.16
+	Hs
		433560 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		MUC1_HUMAN (125-417): 5.85e-09: 60.8: 8.19
+	Hs
		411582 LCK_HUMAN (3-169): 3.75e-50: 169: 19.43		MUC1_HUMAN (125-417): 5.85e-09: 60.8: 8.19
+	Hs
		412362 FYN_HUMAN (6-160): 4.63e-46: 159: 20.73		MAGE1_HUMAN (139-488): 1.2e-09: 62.8: 11.05
+	Hs
		522749 SRC_HUMAN (6-166): 2.04e-43: 152: 18.82		MUC1_HUMAN (125-417): 5.85e-09: 60.8: 8.19