HitPredict

Interactor 1: ZFYV9 (O95405)
Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)
Gene: ZFYVE9

Interactor 2: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.751

Property	Details
Experiments	25416956, 26186194, 27880917, 28514442, 33961781, 15231748, 24366813
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019904 - protein domain specific binding GO:0032991 - protein-containing complex GO:0046872 - metal ion binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1425 Hs			1 323
+	Hs
		313520 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		313521 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Hs
		737894 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		PP1G_HUMAN (1-323): 0: 603: 100.00
+	Hs
		905987 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		906513 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Dm
		819213 Q7K9H6_DROME (232-1421): 0: 897: 29.63		PP11_DROME (5-323): 0: 569: 88.92
+	Dm
		819268 Q7K9H6_DROME (232-1421): 0: 897: 29.63		PP1B_DROME (1-323): 0: 552: 82.48
+	Dm
		524621 Q7K9H6_DROME (232-1421): 0: 897: 29.63		PP12_DROME (5-303): 0: 551: 93.31
+	Dm
		819288 Q960V6_DROME (232-1421): 0: 893: 29.55		PP1B_DROME (1-323): 0: 552: 82.48
+	Dm
		524637 Q960V6_DROME (232-1421): 0: 893: 29.55		PP12_DROME (5-303): 0: 551: 93.31
+	Dm
		984178 Q7K9H6_DROME (232-1421): 0: 897: 29.63		PP13_DROME (5-303): 0: 547: 91.64
+	Dm
		984188 Q960V6_DROME (232-1421): 0: 893: 29.55		PP13_DROME (5-303): 0: 547: 91.64
+	Hs
		905981 FGD5_HUMAN (151-872): 3.46e-92: 330: 14.82		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		906509 FGD5_HUMAN (151-872): 3.46e-92: 330: 14.82		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Hs
		906144 ZFYV1_HUMAN (549-756): 8.36e-37: 152: 21.03		PP1A_HUMAN (1-323): 0: 579: 90.66