Interactor 1: ZFYV9 (O95405)
Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)
Gene: ZFYVE9
Interactor 2: SMAD2 (Q15796)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2)
Gene: SMAD2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.981 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15356634, 33961781, 11094085, 18729074, 9865696, 18511908, 16916642, 15231748, 15613484, 17272273, 10615055 |
| Identification Methods | affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation, tandem affinity purification, affinity technology, x-ray crystallography, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | MH2~SARA |
| Common GO terms | GO:0005829 - cytosol GO:0007179 - transforming growth factor beta receptor signaling pathway GO:0032991 - protein-containing complex GO:0046872 - metal ion binding |
| Homologous interactions | 12 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
