HitPredict

Interactor 1: ZFYV9 (O95405)
Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)
Gene: ZFYVE9

Interactor 2: DDR2 (Q16832)
Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)
Gene: DDR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1425 Hs			1 855
+	Hs
		313542 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		NTRK2_HUMAN (498-850): 2.17e-106: 348: 40.50
+	Hs
		313492 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49
+	Hs
		313504 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		FGFR2_HUMAN (522-851): 6.41e-102: 336: 34.42
+	Hs
		313505 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		FGFR4_HUMAN (537-849): 4.35e-98: 325: 34.78
+	Hs
		508079 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49
+	Hs
		601538 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		FGFR2_HUMAN (522-851): 6.41e-102: 336: 34.42
+	Hs
		608024 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		FGFR4_HUMAN (537-849): 4.35e-98: 325: 34.78
+	Hs
		385389 RUFY1_HUMAN (156-763): 1.92e-101: 342: 14.72		NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62
+	Hs
		601507 MTMR3_HUMAN (196-777): 2.87e-71: 263: 13.18		FGFR2_HUMAN (522-851): 6.41e-102: 336: 34.42
+	Hs
		609293 EEA1_HUMAN (2-758): 9.63e-69: 257: 12.42		FGFR3_HUMAN (485-851): 5.88e-101: 333: 31.28
+	Hs
		385054 RUFY3_HUMAN (138-584): 6.08e-63: 224: 11.45		NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62
+	Hs
		665422 RUFY1_HUMAN (156-763): 1.92e-101: 342: 14.72		EPHA3_HUMAN (554-845): 1.09e-54: 206: 38.93
+	Hs
		435676 FGD5_HUMAN (151-872): 3.46e-92: 330: 14.82		IGF1R_HUMAN (535-845): 9.34e-58: 217: 40.13
+	Hs
		159864 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49
+	Hs
		159885 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		FGFR2_HUMAN (522-851): 6.41e-102: 336: 34.42
+	Hs
		159837 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62
+	Hs
		435647 EEA1_HUMAN (2-758): 9.63e-69: 257: 12.42		IGF1R_HUMAN (535-845): 9.34e-58: 217: 40.13
+	Rn
		94275 F1LUA1_RAT (40-758): 1.09e-60: 231: 11.74		INSR_RAT (511-849): 4.34e-54: 206: 37.46
+	Rn
		88876 D4A1J6_RAT (222-758): 6.37e-55: 212: 12.60		INSR_RAT (511-849): 4.34e-54: 206: 37.46
+	Hs
		159843 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		INSR_HUMAN (511-849): 1.55e-55: 210: 37.76