HitPredict

Interactor 1: SVIL (O95425)
Supervillin (Archvillin) (p205/p250)
Gene: SVIL

Interactor 2: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 30344098
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0030496 - midbody and 1 others more... GO:0032154 - cleavage furrow
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2214 Hs			1 323
+	Hs
		313791 SVIL_HUMAN (1-2214): 0: 3444: 100.00		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Hs
		413846 GELS_HUMAN (1714-2122): 2.55e-82: 291: 18.25		PP1G_HUMAN (1-323): 0: 603: 100.00
+	Hs
		737779 FLII_HUMAN (1423-1683): 1.3e-16: 88.8: 17.30		PP1G_HUMAN (1-323): 0: 603: 100.00
+	Hs
		905863 FLII_HUMAN (1423-1683): 1.3e-16: 88.8: 17.30		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		906437 FLII_HUMAN (1423-1683): 1.3e-16: 88.8: 17.30		PP1B_HUMAN (1-322): 0: 560: 86.89