HitPredict

Interactor 1: SVIL (O95425)
Supervillin (Archvillin) (p205/p250)
Gene: SVIL

Interactor 2: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0015629 - actin cytoskeleton
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2214 Hs			1 793
+	Hs
		313863 SVIL_HUMAN (1-2214): 0: 3444: 100.00		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		313766 SVIL_HUMAN (1-2214): 0: 3444: 100.00		MYH11_HUMAN (2-686): 1.62e-23: 109: 9.77
+	Hs
		313764 SVIL_HUMAN (1-2214): 0: 3444: 100.00		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		313906 SVIL_HUMAN (1-2214): 0: 3444: 100.00		MYH13_HUMAN (1-698): 3.34e-21: 101: 12.00
+	Hs
		313829 SVIL_HUMAN (1-2214): 0: 3444: 100.00		SYCP1_HUMAN (202-788): 3.32e-15: 82.2: 11.41
+	Hs
		148246 SVIL_HUMAN (1-2214): 0: 3444: 100.00		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		313887 SVIL_HUMAN (1-2214): 0: 3444: 100.00		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		414016 GELS_HUMAN (1714-2122): 2.55e-82: 291: 18.25		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		768435 CAPG_HUMAN (1431-1682): 5.46e-74: 253: 20.31		GRDN_HUMAN (28-793): 9.97e-36: 148: 12.77
+	Hs
		73016 B4DU58_HUMAN (1431-1682): 5.68e-74: 252: 20.31		GRDN_HUMAN (28-793): 9.97e-36: 148: 12.77
+	Hs
		413844 GELS_HUMAN (1714-2122): 2.55e-82: 291: 18.25		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		148285 GELS_HUMAN (1714-2122): 2.55e-82: 291: 18.25		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		984572 FLII_HUMAN (1423-1683): 1.3e-16: 88.8: 17.30		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		260679 AVIL_HUMAN (1436-1775): 1.35e-33: 143: 19.83		MYO5A_HUMAN (42-632): 2.15e-24: 112: 15.29
+	Hs
		1023209 FLII_HUMAN (1423-1683): 1.3e-16: 88.8: 17.30		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		260676 AVIL_HUMAN (1436-1775): 1.35e-33: 143: 19.83		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		724803 FLII_HUMAN (1423-1683): 1.3e-16: 88.8: 17.30		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		1023243 FLII_HUMAN (1423-1683): 1.3e-16: 88.8: 17.30		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38