Interactor 1: BAG4 (O95429)
BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains)
Gene: BAG4

Interactor 2: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.936

The method score is based on:

Property Details
Experiments 11909948, 29568061, 32296183, 25036637, unassigned1304, unassigned1655
Identification Methods pull down, affinity chromatography technology, two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BAG~HSP70
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 457
Hs

1 646
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024