HitPredict

Interactor 1: BAG4 (O95429)
BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains)
Gene: BAG4

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 457 Hs			1 504
+	Hs
		125067 BAG4_HUMAN (1-457): 0: 698: 100.00		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		324269 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		809011 BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		324607 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83