HitPredict

Interactor 1: BAG4 (O95429)
BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains)
Gene: BAG4

Interactor 2: Q96BE0 (Q96BE0)
Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8)
Gene: Q96BE0

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	25036637
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	BAG~HSP70
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 457 Hs			1 269
+	Hs
		314010 BAG4_HUMAN (1-457): 0: 698: 100.00		HS71L_HUMAN (1-269): 2.79e-134: 395: 76.58
+	Hs
		313996 BAG4_HUMAN (1-457): 0: 698: 100.00		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		314025 BAG4_HUMAN (1-457): 0: 698: 100.00		HSP72_HUMAN (1-269): 1.82e-126: 374: 78.07
+	Hs
		314001 BAG4_HUMAN (1-457): 0: 698: 100.00		HSP76_HUMAN (1-269): 5.75e-126: 373: 69.15
+	Hs
		314060 BAG4_HUMAN (1-457): 0: 698: 100.00		Q53FC7_HUMAN (1-269): 5.5e-126: 373: 68.77
+	Hs
		72230 BAG4_HUMAN (1-457): 0: 698: 100.00		B3KTT5_HUMAN (1-269): 3.06e-126: 368: 78.07
+	Mm
		571864 BAG4_MOUSE (1-457): 0: 611: 82.79		HS71B_MOUSE (1-269): 4.29e-130: 384: 77.70
+	Dm
		505107 Q9VU81_DROME (352-456): 4.39e-29: 122: 40.74		HSP7D_DROME (1-235): 1.12e-128: 380: 82.55
+	Dm
		65601 A8JNS4_DROME (352-456): 6.34e-29: 121: 40.74		HSP7D_DROME (1-235): 1.12e-128: 380: 82.55
+	Hs
		324256 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		HS71L_HUMAN (1-269): 2.79e-134: 395: 76.58
+	Mm
		926166 BAG3_MOUSE (350-457): 8.44e-24: 106: 45.95		HSP7C_MOUSE (1-269): 1.33e-130: 385: 99.63
+	Mm
		571868 BAG3_MOUSE (350-457): 8.44e-24: 106: 45.95		HS71B_MOUSE (1-269): 4.29e-130: 384: 77.70
+	Hs
		324195 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		324561 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		Q96IS6_HUMAN (1-269): 3.32e-130: 382: 100.00
+	Hs
		324190 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		HS71A_HUMAN (1-269): 2.24e-126: 374: 78.44
+	Hs
		324298 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		HSP72_HUMAN (1-269): 1.82e-126: 374: 78.07
+	Hs
		324216 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		HSP76_HUMAN (1-269): 5.75e-126: 373: 69.15
+	Hs
		324435 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		Q53FC7_HUMAN (1-269): 5.5e-126: 373: 68.77
+	Hs
		72231 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		B3KTT5_HUMAN (1-269): 3.06e-126: 368: 78.07
+	Hs
		324550 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		Q96BE0_HUMAN (1-269): 3.21e-125: 358: 100.00