Interactor 1: AHSA1 (O95433)
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1) (p38)
Gene: AHSA1

Interactor 2: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.985

The method score is based on:

Property Details
Experiments 24462205, 22504172, 26804907, 27353360, 25486457, 27187154, 12504007, 35271311, 20159553, 22315411, 19875381, 20226818, 26693507, 33571422, 25036637, 12604615
Identification Methods affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Aha1_N~HSP90, AHSA1~HSP90
Common GO terms GO:0005829 - cytosol
GO:0006457 - protein folding
GO:0070062 - extracellular exosome
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 338
Hs

1 732
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Sp
+ Sc
+ Sc
+ Sc
+ Sc
+ Dm

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Last updated: 15 Jul 2024