HitPredict

Interactor 1: CENPK (O94494)
Inner kinetochore subunit sim4 (CENP-K homolog) (Constitutive centromere-associated network protein sim4) (Silencing in the middle of the centromere protein 4)
Gene: sim4

Interactor 2: CENPI (P87227)
Inner kinetochore subunit mis6 (CENP-I homolog) (Constitutive centromere-associated network protein mis6) (Sim4 complex subunit mis6)
Gene: mis6

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.90 0.796

The method score is based on:

Property Details
Experiments 12719471, 16079914, 21445296
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CENP-I~CENP-K
Common GO terms GO:0000070 - mitotic sister chromatid segregation
GO:0000779 - condensed chromosome, centromeric region
GO:0000939 - inner kinetochore
GO:0005634 - nucleus
GO:0031511 - Mis6-Sim4 complex
and 1 others

more...
Homologous interactions 0

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Last updated: 11Aug2025