HitPredict

Interactor 1: ATS2 (O95450)
A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS 2) (ADAM-TS2) (ADAMTS-2) (EC 3.4.24.14) (Procollagen I N-proteinase) (PC I-NP) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen N-endopeptidase) (pNPI)
Gene: ADAMTS2

Interactor 2: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1211 Hs			1 222
+	Hs
		533021 ATS14_HUMAN (29-1189): 0: 808: 51.98		PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00
+	Hs
		532946 ADAM9_HUMAN (77-742): 1.77e-144: 458: 19.86		PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00
+	Hs
		533101 ADA21_HUMAN (68-741): 1.43e-112: 370: 17.50		PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00
+	Hs
		1168366 THSD4_HUMAN (857-1098): 1.3e-48: 190: 28.21		PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20
+	Hs
		532990 THSD4_HUMAN (857-1098): 1.3e-48: 190: 28.21		PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00
+	Hs
		1292817 ATS7_HUMAN (611-1197): 7.64e-13: 75.7: 15.21		PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20
+	Hs
		533102 ATS7_HUMAN (611-1197): 7.64e-13: 75.7: 15.21		PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00
+	Hs
		533096 ATS1_HUMAN (979-1077): 6.56e-12: 72.2: 20.00		PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00
+	Hs
		1356546 ATS7_HUMAN (611-1197): 7.64e-13: 75.7: 15.21		PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30