HitPredict

Interactor 1: PSMG1 (O95456)
Proteasome assembly chaperone 1 (PAC-1) (Chromosome 21 leucine-rich protein) (C21-LRP) (Down syndrome critical region protein 2)
Gene: PSMG1

Interactor 2: PSB1 (P20618)
Proteasome subunit beta type-1 (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain)
Gene: PSMB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 288 Hs			1 241
+	Hs
		314745 PSMG1_HUMAN (1-288): 0: 555: 100.00		PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94
+	Hs
		156188 PSMG1_HUMAN (1-288): 0: 555: 100.00		PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54
+	Hs
		314750 PSMG1_HUMAN (1-288): 0: 555: 100.00		PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91
+	Hs
		314733 PSMG1_HUMAN (1-288): 0: 555: 100.00		PSA4_HUMAN (8-240): 1.49e-75: 231: 17.72
+	Hs
		314736 PSMG1_HUMAN (1-288): 0: 555: 100.00		PSA5_HUMAN (16-240): 7.6e-75: 228: 16.67
+	Hs
		314738 PSMG1_HUMAN (1-288): 0: 555: 100.00		PSB6_HUMAN (34-236): 8.15e-56: 180: 21.68
+	Hs
		314746 PSMG1_HUMAN (1-288): 0: 555: 100.00		PSB2_HUMAN (40-233): 2.78e-09: 57: 24.62