HitPredict

Interactor 1: FMNL1 (O95466)
Formin-like protein 1 (CLL-associated antigen KW-13) (Leukocyte formin)
Gene: FMNL1

Interactor 2: RND2 (P52198)
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
Gene: RND2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Drf_FH3~Ras, Drf_GBD~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1100 Hs			1 227
+	Hs
		314854 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03
+	Hs
		314858 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25
+	Hs
		900815 FMNL2_HUMAN (1-1097): 0: 834: 57.31		RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03
+	Hs
		314855 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RB11A_HUMAN (3-224): 7.25e-77: 232: 21.08
+	Hs
		314838 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RAC2_HUMAN (8-195): 4.31e-76: 229: 40.43
+	Hs
		314860 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RHOG_HUMAN (7-193): 2.82e-75: 227: 41.71
+	Hs
		436466 FMNL2_HUMAN (1-1097): 0: 834: 57.31		RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11
+	Hs
		925531 FMNL2_HUMAN (1-1097): 0: 834: 57.31		RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25
+	Hs
		314856 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RHOB_HUMAN (7-184): 9.27e-58: 182: 46.63
+	Hs
		120260 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RHOD_HUMAN (9-191): 9.02e-55: 176: 43.48
+	Hs
		915901 FMNL2_HUMAN (1-1097): 0: 834: 57.31		RHOB_HUMAN (7-184): 9.27e-58: 182: 46.63
+	Hs
		314892 FMNL1_HUMAN (1-1100): 0: 849: 100.00		RHOF_HUMAN (9-191): 9.16e-51: 165: 43.01
+	Hs
		120589 FMNL2_HUMAN (1-1097): 0: 834: 57.31		RHOD_HUMAN (9-191): 9.02e-55: 176: 43.48
+	Dm
		776921 FRL_DROME (19-1088): 0: 650: 36.85		RAC1_DROME (8-195): 8.84e-77: 231: 40.43
+	Hs
		925768 FHOD1_HUMAN (185-1099): 1.49e-138: 449: 16.22		RAC1_HUMAN (8-194): 1.25e-78: 235: 42.25
+	Hs
		900661 FMNL3_HUMAN (1-506): 6.36e-130: 423: 60.90		RHOA_HUMAN (9-193): 2.25e-83: 248: 47.03
+	Hs
		545484 FMNL3_HUMAN (1-506): 6.36e-130: 423: 60.90		RAC2_HUMAN (8-195): 4.31e-76: 229: 40.43
+	Hs
		436333 INF2_HUMAN (181-1063): 2.53e-120: 402: 20.27		RHOC_HUMAN (9-193): 3.15e-81: 242: 48.11
+	Hs
		545409 INF2_HUMAN (181-1063): 2.53e-120: 402: 20.27		RAC2_HUMAN (8-195): 4.31e-76: 229: 40.43
+	Hs
		120464 INF2_HUMAN (181-1063): 2.53e-120: 402: 20.27		RHOD_HUMAN (9-191): 9.02e-55: 176: 43.48