HitPredict

Interactor 1: SGPL1 (O95470)
Sphingosine-1-phosphate lyase 1 (S1PL) (SP-lyase 1) (SPL 1) (hSPL) (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase)
Gene: SGPL1

Interactor 2: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24189400, 23956138
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 568 Hs			1 1210
+	Hs
		314939 SGPL1_HUMAN (1-568): 0: 618: 100.00		ERBB2_HUMAN (5-1200): 0: 1111: 48.49