HitPredict

Interactor 1: CBX6 (O95503)
Chromobox protein homolog 6
Gene: CBX6

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21282530
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 2115
+	Hs
		1061256 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1061250 SUV92_HUMAN (9-226): 1.04e-54: 188: 15.53		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1061215 MPP8_HUMAN (6-339): 4.19e-48: 177: 14.91		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1061293 CDYL_HUMAN (2-275): 6.83e-44: 163: 17.08		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		203688 SUV91_HUMAN (11-222): 8.35e-36: 137: 17.21		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		800381 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1027002 CBX3_HUMAN (9-121): 1.26e-25: 104: 24.56		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1059152 CBX2_HUMAN (161-394): 3.76e-13: 72.9: 21.46		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		123238 CBX4_HUMAN (1-362): 3.71e-34: 135: 23.28		CENPE_HUMAN (694-2076): 2.24e-41: 170: 9.63
+	Hs
		327827 CBX7_HUMAN (1-207): 2.43e-45: 159: 33.33		TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04
+	Hs
		969586 CBX2_HUMAN (161-394): 3.76e-13: 72.9: 21.46		CENPE_HUMAN (694-2076): 2.24e-41: 170: 9.63
+	Hs
		123203 CBX4_HUMAN (1-362): 3.71e-34: 135: 23.28		CENPF_HUMAN (1458-2037): 1.6e-10: 69.3: 9.97