HitPredict

Interactor 1: CBX6 (O95503)
Chromobox protein homolog 6
Gene: CBX6

Interactor 2: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	21047797, 21282530
Identification Methods	unspecified method, x-ray crystallography, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 136
+	Mm
		952770 CBX6_MOUSE (1-393): 3.2e-126: 372: 88.86		H33_MOUSE (1-136): 4.53e-61: 185: 93.38
+	Hs
		316000 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		316012 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		316070 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		316055 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		H37_HUMAN (1-136): 1.11e-58: 179: 94.12
+	Mm
		952774 CBX8_MOUSE (1-393): 7.89e-80: 252: 32.43		H33_MOUSE (1-136): 4.53e-61: 185: 93.38
+	Hs
		935259 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		1086325 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H31T_HUMAN (1-136): 2.65e-61: 186: 100.00
+	Hs
		952637 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		1174664 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H32_HUMAN (1-136): 1.34e-60: 184: 96.32
+	Hs
		828384 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		CENPA_HUMAN (9-133): 3.54e-44: 142: 49.24
+	Dm
		356070 PC_DROME (10-393): 7.49e-58: 196: 21.04		H3_DROME (1-136): 1.34e-60: 184: 96.32
+	Hs
		935237 SUV92_HUMAN (9-226): 1.04e-54: 188: 15.53		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		952627 SUV92_HUMAN (9-226): 1.04e-54: 188: 15.53		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Hs
		935156 MPP8_HUMAN (6-339): 4.19e-48: 177: 14.91		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		952579 MPP8_HUMAN (6-339): 4.19e-48: 177: 14.91		H33_HUMAN (1-136): 4.53e-61: 185: 93.38
+	Dm
		356085 RHINO_DROME (3-331): 1.92e-50: 177: 17.16		H3_DROME (1-136): 1.34e-60: 184: 96.32
+	Sp
		457180 CHP1_SCHPO (7-306): 1.83e-49: 181: 14.91		H31_SCHPO (1-136): 4.67e-59: 180: 88.97
+	Hs
		935387 CDYL_HUMAN (2-275): 6.83e-44: 163: 17.08		H31_HUMAN (1-136): 6.88e-62: 187: 97.06
+	Hs
		952709 CDYL_HUMAN (2-275): 6.83e-44: 163: 17.08		H33_HUMAN (1-136): 4.53e-61: 185: 93.38