HitPredict

Interactor 1: CBX6 (O95503)
Chromobox protein homolog 6
Gene: CBX6

Interactor 2: BCOR (Q6W2J9)
BCL-6 corepressor (BCoR)
Gene: BCOR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 1755
+	Hs
		1167316 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		BCOR_HUMAN (1-1755): 0: 2385: 100.00
+	Hs
		327848 CBX7_HUMAN (1-207): 2.43e-45: 159: 33.33		BCOR_HUMAN (1-1755): 0: 2385: 100.00
+	Hs
		123268 CBX4_HUMAN (1-362): 3.71e-34: 135: 23.28		BCOR_HUMAN (1-1755): 0: 2385: 100.00
+	Hs
		800429 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		BCOR_HUMAN (1-1755): 0: 2385: 100.00
+	Hs
		1027071 CBX3_HUMAN (9-121): 1.26e-25: 104: 24.56		BCOR_HUMAN (1-1755): 0: 2385: 100.00
+	Hs
		316049 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		BCORL_HUMAN (1025-1743): 3.64e-88: 321: 34.63
+	Hs
		257534 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		ANR17_HUMAN (1289-1753): 3.43e-67: 254: 13.21
+	Hs
		1125904 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		BCORL_HUMAN (1025-1743): 3.64e-88: 321: 34.63
+	Hs
		316086 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		ANKH1_HUMAN (1155-1749): 2.19e-52: 206: 13.64
+	Hs
		1334148 CDY2_HUMAN (6-275): 1.02e-56: 196: 17.96		EHMT1_HUMAN (1226-1631): 1.56e-64: 244: 15.87
+	Hs
		1331975 SUV92_HUMAN (9-226): 1.04e-54: 188: 15.53		EHMT1_HUMAN (1226-1631): 1.56e-64: 244: 15.87
+	Hs
		1027031 CBX3_HUMAN (9-121): 1.26e-25: 104: 24.56		BCORL_HUMAN (1025-1743): 3.64e-88: 321: 34.63
+	Hs
		1304468 MPP8_HUMAN (6-339): 4.19e-48: 177: 14.91		EHMT1_HUMAN (1226-1631): 1.56e-64: 244: 15.87
+	Hs
		203794 SUV91_HUMAN (11-222): 8.35e-36: 137: 17.21		EHMT1_HUMAN (1226-1631): 1.56e-64: 244: 15.87
+	Hs
		800530 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		EHMT1_HUMAN (1226-1631): 1.56e-64: 244: 15.87
+	Mm
		1125433 Q9DCC5_MOUSE (9-121): 1.26e-25: 104: 24.56		EHMT1_MOUSE (1226-1635): 8.01e-66: 248: 15.31
+	Hs
		1027268 CBX3_HUMAN (9-121): 1.26e-25: 104: 24.56		EHMT1_HUMAN (1226-1631): 1.56e-64: 244: 15.87
+	Hs
		800503 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		BARD1_HUMAN (1144-1611): 3.52e-62: 230: 19.72
+	Hs
		1027218 CBX3_HUMAN (9-121): 1.26e-25: 104: 24.56		BARD1_HUMAN (1144-1611): 3.52e-62: 230: 19.72
+	Hs
		1304463 MPP8_HUMAN (6-339): 4.19e-48: 177: 14.91		MPP8_HUMAN (1012-1706): 1.51e-15: 84.9: 10.00