HitPredict

Interactor 1: CBX6 (O95503)
Chromobox protein homolog 6
Gene: CBX6

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	18927235
Identification Methods	protein complementation assay, bimolecular fluorescence complementation
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 136
+	Mm
		952770 CBX6_MOUSE (1-393): 3.2e-126: 372: 88.86		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Hs
		316000 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		316040 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		316012 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		316055 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		H37_HUMAN (1-136): 3.26e-59: 181: 97.06
+	Mm
		952774 CBX8_MOUSE (1-393): 7.89e-80: 252: 32.43		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Hs
		935259 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1086325 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		1174664 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		952637 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		828384 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Dm
		356070 PC_DROME (10-393): 7.49e-58: 196: 21.04		H3_DROME (1-136): 3.73e-61: 186: 100.00
+	Hs
		935237 SUV92_HUMAN (9-226): 1.04e-54: 188: 15.53		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952627 SUV92_HUMAN (9-226): 1.04e-54: 188: 15.53		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		935156 MPP8_HUMAN (6-339): 4.19e-48: 177: 14.91		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Dm
		356085 RHINO_DROME (3-331): 1.92e-50: 177: 17.16		H3_DROME (1-136): 3.73e-61: 186: 100.00
+	Hs
		952579 MPP8_HUMAN (6-339): 4.19e-48: 177: 14.91		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Sp
		457180 CHP1_SCHPO (7-306): 1.83e-49: 181: 14.91		H31_SCHPO (1-136): 2.22e-59: 181: 91.91
+	Hs
		935387 CDYL_HUMAN (2-275): 6.83e-44: 163: 17.08		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952709 CDYL_HUMAN (2-275): 6.83e-44: 163: 17.08		H33_HUMAN (1-136): 1.59e-61: 186: 97.06