HitPredict

Interactor 1: CBX6 (O95503)
Chromobox protein homolog 6
Gene: CBX6

Interactor 2: SCML2 (Q9UQR0)
Sex comb on midleg-like protein 2
Gene: SCML2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21282530
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0031519 - PcG protein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 700
+	Hs
		1335794 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		SCML2_HUMAN (1-700): 0: 777: 100.00
+	Dm
		639977 PC_DROME (10-393): 7.49e-58: 196: 21.04		SCM_DROME (22-694): 2.52e-179: 535: 30.81
+	Hs
		316088 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		PHC2_HUMAN (211-697): 1.07e-85: 289: 15.99
+	Hs
		1220894 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		PHC2_HUMAN (211-697): 1.07e-85: 289: 15.99
+	Hs
		316005 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		PHC1_HUMAN (455-696): 4.09e-47: 181: 21.57
+	Dr
		1193375 Q804D1_DANRE (1-385): 1.19e-77: 250: 24.21		PHC2_DANRE (253-697): 2.86e-78: 269: 17.04
+	Hs
		316103 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		PHC3_HUMAN (445-697): 4.59e-41: 163: 20.30
+	Hs
		69543 B0QXZ6_HUMAN (1-393): 3.76e-108: 325: 95.42		PHC1_HUMAN (455-696): 4.09e-47: 181: 21.57
+	Hs
		316200 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		SCML1_HUMAN (471-698): 6.13e-32: 128: 29.54
+	Hs
		316124 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		SCMH1_HUMAN (7-131): 9.67e-23: 105: 32.03
+	Hs
		327853 CBX7_HUMAN (1-207): 2.43e-45: 159: 33.33		PHC2_HUMAN (211-697): 1.07e-85: 289: 15.99
+	Hs
		943094 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		PHC1_HUMAN (455-696): 4.09e-47: 181: 21.57
+	Hs
		1242737 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		PHC3_HUMAN (445-697): 4.59e-41: 163: 20.30
+	Dm
		639978 PC_DROME (10-393): 7.49e-58: 196: 21.04		SMBT_DROME (6-336): 1.11e-47: 183: 22.07
+	Hs
		1335791 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		SCML1_HUMAN (471-698): 6.13e-32: 128: 29.54
+	Dm
		639953 PC_DROME (10-393): 7.49e-58: 196: 21.04		PHP_DROME (497-697): 7.94e-39: 156: 25.37
+	Hs
		1292155 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		SCMH1_HUMAN (7-131): 9.67e-23: 105: 32.03
+	Dm
		639970 PC_DROME (10-393): 7.49e-58: 196: 21.04		Q9NF31_DROME (486-697): 6.82e-37: 150: 23.61
+	Hs
		327838 CBX7_HUMAN (1-207): 2.43e-45: 159: 33.33		PHC1_HUMAN (455-696): 4.09e-47: 181: 21.57
+	Hs
		327855 CBX7_HUMAN (1-207): 2.43e-45: 159: 33.33		PHC3_HUMAN (445-697): 4.59e-41: 163: 20.30