HitPredict

Interactor 1: KLF8 (O95600)
Krueppel-like factor 8 (Basic krueppel-like factor 3) (Zinc finger protein 741)
Gene: KLF8

Interactor 2: EMSY (Q7Z589)
BRCA2-interacting transcriptional repressor EMSY
Gene: EMSY

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 359 Hs			1 1322
+	Hs
		1190890 KLF12_HUMAN (44-356): 6.24e-85: 264: 42.58		EMSY_HUMAN (1-1322): 5.68e-132: 441: 100.00
+	Hs
		884192 KLF3_HUMAN (22-356): 2.98e-51: 175: 34.19		EMSY_HUMAN (1-1322): 5.68e-132: 441: 100.00
+	Hs
		1190868 KLF6_HUMAN (225-356): 1.11e-45: 159: 58.33		EMSY_HUMAN (1-1322): 5.68e-132: 441: 100.00
+	Hs
		316970 KLF8_HUMAN (1-356): 5.7e-92: 281: 100.00		MINT_HUMAN (72-1304): 8.31e-15: 82.4: 10.57
+	Hs
		152569 KLF8_HUMAN (1-356): 5.7e-92: 281: 100.00		KMT2D_HUMAN (261-1253): 1.13e-12: 75.2: 7.65
+	Hs
		72699 KLF8_HUMAN (1-356): 5.7e-92: 281: 100.00		B4DET5_HUMAN (148-938): 2.35e-12: 73.7: 12.66
+	Hs
		65035 KLF8_HUMAN (1-356): 5.7e-92: 281: 100.00		P121C_HUMAN (148-938): 7.82e-12: 72.2: 12.28
+	Hs
		316913 KLF8_HUMAN (1-356): 5.7e-92: 281: 100.00		ARID2_HUMAN (125-705): 7.19e-11: 69.4: 16.85
+	Hs
		1056958 ZN251_HUMAN (69-333): 1.28e-63: 216: 12.00		MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96
+	Hs
		435145 SP1_HUMAN (90-358): 1.01e-66: 226: 30.48		TITIN_HUMAN (94-1299): 1.78e-13: 78.2: 9.72
+	Hs
		152621 KLF3_HUMAN (22-356): 2.98e-51: 175: 34.19		KMT2D_HUMAN (261-1253): 1.13e-12: 75.2: 7.65
+	Hs
		204195 KLF4_HUMAN (105-356): 4.72e-49: 174: 32.56		KMT2C_HUMAN (136-1005): 1.04e-12: 75.6: 6.91
+	Hs
		152558 KLF4_HUMAN (105-356): 4.72e-49: 174: 32.56		KMT2D_HUMAN (261-1253): 1.13e-12: 75.2: 7.65
+	Hs
		884182 KLF3_HUMAN (22-356): 2.98e-51: 175: 34.19		ARID2_HUMAN (125-705): 7.19e-11: 69.4: 16.85
+	Hs
		204194 KLF4_HUMAN (105-356): 4.72e-49: 174: 32.56		HUWE1_HUMAN (272-823): 7.43e-11: 69.4: 14.11
+	Hs
		1147475 KLF6_HUMAN (225-356): 1.11e-45: 159: 58.33		ARID2_HUMAN (125-705): 7.19e-11: 69.4: 16.85
+	Hs
		1046715 KLF5_HUMAN (267-356): 1.18e-41: 152: 78.89		KMT2C_HUMAN (136-1005): 1.04e-12: 75.6: 6.91
+	Hs
		152643 KLF5_HUMAN (267-356): 1.18e-41: 152: 78.89		KMT2D_HUMAN (261-1253): 1.13e-12: 75.2: 7.65
+	Hs
		1046698 KLF5_HUMAN (267-356): 1.18e-41: 152: 78.89		ARID2_HUMAN (125-705): 7.19e-11: 69.4: 16.85
+	Hs
		152697 KLF15_HUMAN (272-356): 1.38e-31: 125: 63.53		KMT2D_HUMAN (261-1253): 1.13e-12: 75.2: 7.65