HitPredict

Interactor 1: RPA1 (O95602)
DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194)
Gene: POLR1A

Interactor 2: RPAB1 (P19388)
DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (DNA-directed RNA polymerase II 23 kDa polypeptide) (DNA-directed RNA polymerase II subunit E) (RPB5 homolog) (XAP4)
Gene: POLR2E

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 28514442, 24981860, 33961781, 35271311, 26496610, 36271492, 19214185
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_1~RNA_pol_Rpb5_C, RNA_pol_Rpb1_1~RNA_pol_Rpb5_N, RNA_pol_Rpb1_5~RNA_pol_Rpb5_C, RNA_pol_Rpb1_5~RNA_pol_Rpb5_N
Common GO terms GO:0001054 - RNA polymerase I activity
GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005654 - nucleoplasm
GO:0005736 - RNA polymerase I complex
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1720
Hs

1 210
+ Sc
+ Hv
+ Bt
+ Hs
+ At
+ Sp
+ Hs
+ Sc
+ Sc
+ At
+ At
+ At
+ At
+ Hv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024