HitPredict

Interactor 1: RPA1 (O95602)
DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194)
Gene: POLR1A

Interactor 2: RPAB3 (P52434)
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (DNA-directed RNA polymerase II subunit H) (DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide) (RPB17) (RPB8 homolog) (hRPB8)
Gene: POLR2H

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.922

The method score is based on:

Property Details
Experiments 24981860, 35271311, 26496610, 36271492, 19214185
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_3~RNA_pol_Rpb8, RNA_pol_Rpb1_4~RNA_pol_Rpb8, RNA_pol_Rpb1_5~RNA_pol_Rpb8
Common GO terms GO:0001054 - RNA polymerase I activity
GO:0005654 - nucleoplasm
GO:0005736 - RNA polymerase I complex
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1720
Hs

1 150
+ Hs
+ Sc
+ Hs
+ Bt
+ Hs
+ Sp
+ Sc
+ Sc
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024