Interactor 1: RPA1 (O95602)
DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194)
Gene: POLR1A

Interactor 2: RPB11 (P52435)
DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit)
Gene: POLR2J

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24981860
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_L_2~RNA_pol_Rpb1_1, RNA_pol_L_2~RNA_pol_Rpb1_2, RNA_pol_L_2~RNA_pol_Rpb1_3
Common GO terms GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005654 - nucleoplasm
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1720
Hs

1 117
+ Hs
+ Sc
+ Bt
+ Hs
+ Sp
+ Sc
+ Hs
+ Hs
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+ At
+ At

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Last updated: 15 Jul 2024