Interactor 1: RPA1 (O95602)
DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194)
Gene: POLR1A

Interactor 2: RPAB2 (P61218)
DNA-directed RNA polymerases I, II, and III subunit RPABC2 (RNA polymerases I, II, and III subunit ABC2) (DNA-directed RNA polymerase II subunit F) (DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide) (RPABC14.4) (RPB14.4) (RPB6 homolog) (RPC15)
Gene: POLR2F

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.927

The method score is based on:

Property Details
Experiments 26496610, 33961781, 35271311, 24981860, 36271492
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_2~RNA_pol_Rpb6, RNA_pol_Rpb1_3~RNA_pol_Rpb6, RNA_pol_Rpb1_5~RNA_pol_Rpb6
Common GO terms GO:0001054 - RNA polymerase I activity
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005736 - RNA polymerase I complex
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1720
Hs

1 127
+ Sc
+ Bt
+ Hs
+ Sp
+ Sc
+ Hs
+ Sc
+ At
+ At
+ At

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Last updated: 15 Jul 2024