HitPredict

Interactor 1: UBP1 (O94782)
Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (hUBP) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) [Cleaved into: Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment]
Gene: USP1

Interactor 2: FACD2 (Q9BXW9)
Fanconi anemia group D2 protein (Protein FACD2)
Gene: FANCD2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 27986371, 30456385, 31253762, 32510829, 36170365, 36385258, 15694335, 18082604
Identification Methods enzymatic study, pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FancD2~UCH
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 785
Hs

1 1451
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025