Interactor 1: CNOT4 (O95628)
CCR4-NOT transcription complex subunit 4 (EC 2.3.2.27) (CCR4-associated factor 4) (E3 ubiquitin-protein ligase CNOT4) (Potential transcriptional repressor NOT4Hp) (RING-type E3 ubiquitin transferase CNOT4)
Gene: CNOT4

Interactor 2: TTP (P26651)
mRNA decay activator protein ZFP36 (G0/G1 switch regulatory protein 24) (Growth factor-inducible nuclear protein NUP475) (Tristetraprolin) (Zinc finger protein 36) (Zfp-36)
Gene: ZFP36

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29395067
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~zf-CCCH
Common GO terms GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0030014 - CCR4-NOT complex
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 575
Hs

1 326
+ Ce
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024