HitPredict

Interactor 1: STABP (O95630)
STAM-binding protein (EC 3.4.19.-) (Associated molecule with the SH3 domain of STAM) (Endosome-associated ubiquitin isopeptidase)
Gene: STAMBP

Interactor 2: CHMP5 (Q9NZZ3)
Charged multivesicular body protein 5 (Chromatin-modifying protein 5) (SNF7 domain-containing protein 2) (Vacuolar protein sorting-associated protein 60) (Vps60) (hVps60)
Gene: CHMP5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	21988832, 17711858
Identification Methods	two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 424 Hs			1 219
+	Hs
		317748 STABP_HUMAN (1-424): 0: 605: 100.00		CHM4C_HUMAN (6-207): 1.63e-30: 114: 21.18
+	Hs
		208807 STABP_HUMAN (1-424): 0: 605: 100.00		CHM2A_HUMAN (1-192): 1.79e-30: 113: 23.44
+	Hs
		317763 STABP_HUMAN (1-424): 0: 605: 100.00		CHM4B_HUMAN (15-210): 7.62e-30: 112: 21.72
+	Hs
		317760 STABP_HUMAN (1-424): 0: 605: 100.00		CHM4A_HUMAN (1-210): 2.9e-29: 110: 22.33
+	Hs
		317780 STABP_HUMAN (1-424): 0: 605: 100.00		CHMP3_HUMAN (3-200): 3.25e-28: 107: 18.69
+	At
		1129494 AMSH3_ARATH (16-424): 1.09e-152: 443: 29.39		VP601_ARATH (1-219): 2.19e-46: 154: 44.83
+	At
		1257947 AMSH1_ARATH (16-424): 7.05e-154: 446: 25.40		VPS2A_ARATH (1-207): 2e-34: 124: 20.29
+	At
		1129495 AMSH3_ARATH (16-424): 1.09e-152: 443: 29.39		VPS2A_ARATH (1-207): 2e-34: 124: 20.29
+	Dm
		1249813 Q9VA71_DROME (5-424): 8.94e-156: 448: 40.41		CHM4_DROME (2-198): 1.41e-32: 119: 25.25
+	Dm
		1360858 Q9VA71_DROME (5-424): 8.94e-156: 448: 40.41		Q9VBI3_DROME (1-208): 5.77e-28: 107: 20.19
+	Dm
		1360861 Q9VA71_DROME (5-424): 8.94e-156: 448: 40.41		Q9VN02_DROME (3-212): 9.34e-27: 104: 13.81