Interactor 1: NET1 (O95631)
Netrin-1 (Epididymis tissue protein Li 131P)
Gene: NTN1

Interactor 2: DCC (P43146)
Netrin receptor DCC (Colorectal cancer suppressor) (Immunoglobulin superfamily DCC subclass member 1) (Tumor suppressor protein DCC)
Gene: DCC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.922

The method score is based on:

Property Details
Experiments 9950216, 12810718, 20434207, 19721007, 26190107
Identification Methods pull down, affinity chromatography technology, solid phase assay, avexis, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Laminin_EGF~fn3, Laminin_N~fn3
Common GO terms GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0033564 - anterior/posterior axon guidance
GO:0098609 - cell-cell adhesion
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 604
Hs

1 1447
+ Mm
+ Hs
+ Mm
+ Hs
+ Dr
+ Dr
+ Dr
+ Mm
+ Hs
+ Dm
+ Mm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024