HitPredict

Interactor 1: CPSF4 (O95639)
Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog)
Gene: CPSF4

Interactor 2: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29802200
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 269 Hs			1 437
+	Hs
		317813 CPSF4_HUMAN (1-269): 7.46e-105: 307: 100.00		CSTF2_HUMAN (85-177): 1.23e-20: 96.4: 32.26
+	Hs
		317856 CPSF4_HUMAN (1-269): 7.46e-105: 307: 100.00		CSTFT_HUMAN (84-177): 2.89e-20: 95.3: 30.85
+	Dm
		1364313 CPSF4_DROME (1-269): 2.44e-80: 246: 54.11		Q9VE52_DROME (90-177): 5.87e-21: 96.4: 31.82
+	Hs
		1221460 ZC3H3_HUMAN (31-226): 5.83e-38: 143: 25.50		PABP3_HUMAN (4-361): 3.46e-50: 181: 11.86
+	Hs
		516728 MKRN1_HUMAN (36-257): 4.41e-35: 133: 16.79		PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08
+	Hs
		256453 ZC11A_HUMAN (62-232): 3.95e-30: 120: 16.38		PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08
+	Hs
		442571 MKRN1_HUMAN (36-257): 4.41e-35: 133: 16.79		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Hs
		256447 ZC11A_HUMAN (62-232): 3.95e-30: 120: 16.38		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Hs
		1288644 MKRN1_HUMAN (36-257): 4.41e-35: 133: 16.79		PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14
+	Hs
		1031384 ZC3H3_HUMAN (31-226): 5.83e-38: 143: 25.50		PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81
+	Hs
		1031488 MKRN1_HUMAN (36-257): 4.41e-35: 133: 16.79		PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81
+	Hs
		256559 ZC11A_HUMAN (62-232): 3.95e-30: 120: 16.38		PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14
+	Hs
		442248 ZC3HE_HUMAN (61-186): 1.76e-21: 95.4: 22.37		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Hs
		442597 ZC3H4_HUMAN (85-233): 1.1e-19: 90.4: 18.67		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Hs
		1162367 ZC3HE_HUMAN (61-186): 1.76e-21: 95.4: 22.37		PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14
+	Hs
		963580 MKRN1_HUMAN (36-257): 4.41e-35: 133: 16.79		TIAR_HUMAN (97-338): 4.83e-20: 93.1: 14.18
+	Hs
		236119 MKRN1_HUMAN (36-257): 4.41e-35: 133: 16.79		HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55
+	Sp
		195095 YTH1_SCHPO (65-173): 2.56e-32: 118: 54.96		CTF1_SCHPO (105-191): 8.36e-17: 83.3: 24.14
+	Hs
		1295952 ZC3HA_HUMAN (66-166): 6.41e-20: 90.3: 25.00		RBM38_HUMAN (98-195): 1.81e-15: 77.5: 30.61
+	Hs
		235952 ZC3H8_HUMAN (86-187): 3.83e-14: 72.7: 22.12		HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55