HitPredict

Interactor 1: CPSF4 (O95639)
Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog)
Gene: CPSF4

Interactor 2: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 29298432, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 269 Hs			1 953
+	Hs
		256543 ZC11A_HUMAN (62-232): 3.95e-30: 120: 16.38		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		1162350 ZC3HE_HUMAN (61-186): 1.76e-21: 95.4: 22.37		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		1201765 ZC3H4_HUMAN (85-233): 1.1e-19: 90.4: 18.67		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		317830 CPSF4_HUMAN (1-269): 7.46e-105: 307: 100.00		MDC1_HUMAN (9-950): 1.49e-09: 64.4: 9.73
+	Hs
		1201660 MKRN2_HUMAN (62-118): 6.86e-09: 58: 27.59		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		256548 ZC11A_HUMAN (62-232): 3.95e-30: 120: 16.38		THOC2_HUMAN (248-635): 6.8e-20: 98.2: 14.15
+	Hs
		1057014 MKRN1_HUMAN (36-257): 4.41e-35: 133: 16.79		MDC1_HUMAN (9-950): 1.49e-09: 64.4: 9.73
+	Hs
		1162357 ZC3HE_HUMAN (61-186): 1.76e-21: 95.4: 22.37		THOC2_HUMAN (248-635): 6.8e-20: 98.2: 14.15
+	Hs
		1162353 ZC3HE_HUMAN (61-186): 1.76e-21: 95.4: 22.37		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14
+	Hs
		1222825 ZC3HA_HUMAN (66-166): 6.41e-20: 90.3: 25.00		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14