HitPredict

Interactor 1: CPSF4 (O95639)
Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog)
Gene: CPSF4

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 269 Hs			1 530
+	Hs
		317802 CPSF4_HUMAN (1-269): 7.46e-105: 307: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1221421 ZC3H3_HUMAN (31-226): 5.83e-38: 143: 25.50		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269857 MKRN1_HUMAN (36-257): 4.41e-35: 133: 16.79		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		256555 ZC11A_HUMAN (62-232): 3.95e-30: 120: 16.38		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1162361 ZC3HE_HUMAN (61-186): 1.76e-21: 95.4: 22.37		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		370648 MKRN1_HUMAN (36-257): 4.41e-35: 133: 16.79		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		256440 ZC11A_HUMAN (62-232): 3.95e-30: 120: 16.38		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369842 ZC3HE_HUMAN (61-186): 1.76e-21: 95.4: 22.37		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		317807 CPSF4_HUMAN (1-269): 7.46e-105: 307: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487847 ZC3H4_HUMAN (85-233): 1.1e-19: 90.4: 18.67		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59