HitPredict

Interactor 1: NFAC1 (O95644)
Nuclear factor of activated T-cells, cytoplasmic 1 (NF-ATc1) (NFATc1) (NFAT transcription complex cytosolic component) (NF-ATc) (NFATc)
Gene: NFATC1

Interactor 2: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27637333
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 943 Hs			1 654
+	Hs
		587444 NFKB1_HUMAN (380-782): 3.13e-99: 335: 16.59		HS71L_HUMAN (24-647): 0: 922: 63.16
+	Mm
		638457 NFKB1_MOUSE (380-832): 1.07e-103: 347: 15.17		HS71A_MOUSE (26-635): 0: 908: 63.46
+	Hs
		713949 REL_HUMAN (419-924): 3.8e-101: 331: 15.34		HS71L_HUMAN (24-647): 0: 922: 63.16
+	Hs
		503415 NFKB1_HUMAN (380-782): 3.13e-99: 335: 16.59		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		564000 NFKB1_HUMAN (380-782): 3.13e-99: 335: 16.59		HSP76_HUMAN (25-635): 0: 915: 62.54
+	Hs
		501665 NFKB1_HUMAN (380-782): 3.13e-99: 335: 16.59		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		503943 REL_HUMAN (419-924): 3.8e-101: 331: 15.34		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		564060 REL_HUMAN (419-924): 3.8e-101: 331: 15.34		HSP76_HUMAN (25-635): 0: 915: 62.54
+	Hs
		502003 REL_HUMAN (419-924): 3.8e-101: 331: 15.34		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		587480 NFKB1_HUMAN (380-782): 3.13e-99: 335: 16.59		HSP72_HUMAN (25-636): 0: 905: 64.51
+	Hs
		504030 NFAC2_HUMAN (37-937): 4e-88: 303: 40.61		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		502063 NFAC2_HUMAN (37-937): 4e-88: 303: 40.61		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		713945 NFKB2_HUMAN (410-852): 8.77e-79: 277: 17.67		HS71L_HUMAN (24-647): 0: 922: 63.16
+	Hs
		503906 NFKB2_HUMAN (410-852): 8.77e-79: 277: 17.67		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		564057 NFKB2_HUMAN (410-852): 8.77e-79: 277: 17.67		HSP76_HUMAN (25-635): 0: 915: 62.54
+	Hs
		501980 NFKB2_HUMAN (410-852): 8.77e-79: 277: 17.67		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		503938 TF65_HUMAN (408-939): 5.93e-78: 266: 17.86		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		564059 TF65_HUMAN (408-939): 5.93e-78: 266: 17.86		HSP76_HUMAN (25-635): 0: 915: 62.54
+	Hs
		501999 TF65_HUMAN (408-939): 5.93e-78: 266: 17.86		BIP_HUMAN (19-654): 0: 914: 100.00
+	Mm
		978965 TF65_MOUSE (413-939): 5.69e-78: 266: 17.48		HS71A_MOUSE (26-635): 0: 908: 63.46