HitPredict

Interactor 1: NFAC1 (O95644)
Nuclear factor of activated T-cells, cytoplasmic 1 (NF-ATc1) (NFATc1) (NFAT transcription complex cytosolic component) (NF-ATc) (NFATc)
Gene: NFATC1

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15161933
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 943 Hs			1 245
+	Hs
		317946 NFAC1_HUMAN (1-943): 4.64e-146: 459: 100.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		646849 NFAC3_HUMAN (24-940): 7e-106: 355: 34.55		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		926986 NFAC3_HUMAN (24-940): 7e-106: 355: 34.55		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683306 NFAC3_HUMAN (24-940): 7e-106: 355: 34.55		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		587432 NFKB1_HUMAN (380-782): 3.13e-99: 335: 16.59		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		909525 NFAC2_HUMAN (37-937): 4e-88: 303: 40.61		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		646869 NFAC2_HUMAN (37-937): 4e-88: 303: 40.61		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927009 NFAC2_HUMAN (37-937): 4e-88: 303: 40.61		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683321 NFAC2_HUMAN (37-937): 4e-88: 303: 40.61		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		646895 NFAC4_HUMAN (41-937): 1.43e-80: 282: 32.50		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927051 NFAC4_HUMAN (41-937): 1.43e-80: 282: 32.50		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		684004 NFAC3_HUMAN (24-940): 7e-106: 355: 34.55		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		981965 NFAC3_HUMAN (24-940): 7e-106: 355: 34.55		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		904504 NFAC3_HUMAN (24-940): 7e-106: 355: 34.55		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		904526 NFAC2_HUMAN (37-937): 4e-88: 303: 40.61		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		297821 K0754_HUMAN (122-457): 1.85e-21: 103: 12.29		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		297824 K0754_HUMAN (122-457): 1.85e-21: 103: 12.29		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		297815 K0754_HUMAN (122-457): 1.85e-21: 103: 12.29		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		647025 OTOG_HUMAN (2-290): 2.06e-09: 64.1: 10.04		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		683472 OTOG_HUMAN (2-290): 2.06e-09: 64.1: 10.04		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82