HitPredict

Interactor 1: NFAC1 (O95644)
Nuclear factor of activated T-cells, cytoplasmic 1 (NF-ATc1) (NFATc1) (NFAT transcription complex cytosolic component) (NF-ATc) (NFATc)
Gene: NFATC1

Interactor 2: PYR1 (P27708)
Multifunctional protein CAD (Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase) [Includes: Glutamine-dependent carbamoyl phosphate synthase (EC 6.3.5.5); Glutamine amidotransferase (GATase) (GLNase) (EC 3.5.1.2); Ammonium-dependent carbamoyl phosphate synthase (CPS) (CPSase) (EC 6.3.4.16); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]
Gene: CAD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27637333
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 943 Hs			1 2225
+	Hs
		653250 NFAC2_HUMAN (37-937): 4e-88: 303: 40.61		PYR1_HUMAN (1-2225): 0: 2858: 100.00
+	Hs
		653227 NFKB2_HUMAN (410-852): 8.77e-79: 277: 17.67		PYR1_HUMAN (1-2225): 0: 2858: 100.00
+	Hs
		653233 TF65_HUMAN (408-939): 5.93e-78: 266: 17.86		PYR1_HUMAN (1-2225): 0: 2858: 100.00
+	Hs
		653228 RELB_HUMAN (317-856): 1.73e-77: 265: 14.46		PYR1_HUMAN (1-2225): 0: 2858: 100.00
+	Sc
		424519 SEC31_YEAST (27-436): 6.96e-29: 127: 13.50		PYR1_YEAST (1-2223): 0: 2271: 49.41
+	Hs
		513530 NFKB1_HUMAN (380-782): 3.13e-99: 335: 16.59		PYC_HUMAN (367-846): 4.8e-108: 377: 18.84