HitPredict

Interactor 1: NFAC1 (O95644)
Nuclear factor of activated T-cells, cytoplasmic 1 (NF-ATc1) (NFATc1) (NFAT transcription complex cytosolic component) (NF-ATc) (NFATc)
Gene: NFATC1

Interactor 2: CD40L (P29965)
CD40 ligand (CD40-L) (T-cell antigen Gp39) (TNF-related activation protein) (TRAP) (Tumor necrosis factor ligand superfamily member 5) (CD antigen CD154) [Cleaved into: CD40 ligand, membrane form; CD40 ligand, soluble form (sCD40L)]
Gene: CD40LG

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	16099873
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 943 Hs			1 261
+	Hs
		669879 REL_HUMAN (419-924): 3.8e-101: 331: 15.34		CD40L_HUMAN (1-261): 5.82e-116: 334: 100.00
+	Hs
		669883 NFAC2_HUMAN (37-937): 4e-88: 303: 40.61		CD40L_HUMAN (1-261): 5.82e-116: 334: 100.00
+	Hs
		317883 NFAC1_HUMAN (1-943): 4.64e-146: 459: 100.00		TNFA_HUMAN (87-261): 1.96e-52: 172: 21.20
+	Hs
		155683 NFAC3_HUMAN (24-940): 7e-106: 355: 34.55		TNF11_HUMAN (20-261): 1.81e-83: 254: 22.46
+	Hs
		352598 NFAC3_HUMAN (24-940): 7e-106: 355: 34.55		TNFA_HUMAN (87-261): 1.96e-52: 172: 21.20
+	Mm
		420392 NFKB1_MOUSE (380-832): 1.07e-103: 347: 15.17		TNFA_MOUSE (87-261): 6.05e-44: 150: 18.48
+	Mm
		78126 B5B2U4_MOUSE (24-922): 1.07e-100: 341: 35.47		TNFA_MOUSE (87-261): 6.05e-44: 150: 18.48
+	Hs
		352606 NFAC2_HUMAN (37-937): 4e-88: 303: 40.61		TNFA_HUMAN (87-261): 1.96e-52: 172: 21.20
+	Hs
		352617 NFAC4_HUMAN (41-937): 1.43e-80: 282: 32.50		TNFA_HUMAN (87-261): 1.96e-52: 172: 21.20
+	Hs
		352589 TF65_HUMAN (408-939): 5.93e-78: 266: 17.86		TNFA_HUMAN (87-261): 1.96e-52: 172: 21.20
+	Hs
		352584 RELB_HUMAN (317-856): 1.73e-77: 265: 14.46		TNFA_HUMAN (87-261): 1.96e-52: 172: 21.20
+	Hs
		300514 NFAT5_HUMAN (172-923): 2.45e-71: 260: 23.76		TNFA_HUMAN (87-261): 1.96e-52: 172: 21.20
+	Mm
		420398 RELB_MOUSE (390-856): 2.06e-80: 273: 16.08		TNFA_MOUSE (87-261): 6.05e-44: 150: 18.48
+	Mm
		420397 TF65_MOUSE (413-939): 5.69e-78: 266: 17.48		TNFA_MOUSE (87-261): 6.05e-44: 150: 18.48
+	Mm
		420412 NFAT5_MOUSE (172-923): 2.28e-73: 266: 23.72		TNFA_MOUSE (87-261): 6.05e-44: 150: 18.48
+	Hs
		815717 MYO15_HUMAN (32-503): 1.11e-19: 97.6: 10.35		TNFL6_HUMAN (89-261): 6.63e-55: 179: 18.86