HitPredict

Interactor 1: NFAC1 (O95644)
Nuclear factor of activated T-cells, cytoplasmic 1 (NF-ATc1) (NFATc1) (NFAT transcription complex cytosolic component) (NF-ATc) (NFATc)
Gene: NFATC1

Interactor 2: IL2 (P60568)
Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin)
Gene: IL2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	20557936, 12560487
Identification Methods	anti tag coimmunoprecipitation, electrophoretic mobility shift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 943 Hs			1 153
+	Hs
		891386 NFAC3_HUMAN (24-940): 7e-106: 355: 34.55		IL2_HUMAN (1-153): 1.29e-80: 236: 100.00
+	Hs
		891382 REL_HUMAN (419-924): 3.8e-101: 331: 15.34		IL2_HUMAN (1-153): 1.29e-80: 236: 100.00
+	Hs
		891387 NFAC2_HUMAN (37-937): 4e-88: 303: 40.61		IL2_HUMAN (1-153): 1.29e-80: 236: 100.00
+	Mm
		381344 NFAC2_MOUSE (37-937): 5.28e-91: 311: 39.55		IL2_MOUSE (1-151): 6.75e-71: 212: 57.23
+	Hs
		891381 TF65_HUMAN (408-939): 5.93e-78: 266: 17.86		IL2_HUMAN (1-153): 1.29e-80: 236: 100.00
+	Mm
		381343 TF65_MOUSE (413-939): 5.69e-78: 266: 17.48		IL2_MOUSE (1-151): 6.75e-71: 212: 57.23