HitPredict

Interactor 1: VATG2 (O95670)
V-type proton ATPase subunit G 2 (V-ATPase subunit G 2) (V-ATPase 13 kDa subunit 2) (Vacuolar proton pump subunit G 2)
Gene: ATP6V1G2

Interactor 2: VPP3 (Q13488)
V-type proton ATPase 116 kDa subunit a 3 (V-ATPase 116 kDa subunit a 3) (Osteoclastic proton pump 116 kDa subunit) (OC-116 kDa) (OC116) (T-cell immune regulator 1) (T-cell immune response cDNA7 protein) (TIRC7) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3)
Gene: TCIRG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	V-ATPase_G~V_ATPase_I
Common GO terms	GO:0046961 - proton-transporting ATPase activity, rotational mechanism
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 118 Hs			1 830
+	Mm
		1321784 VATG1_MOUSE (1-118): 5.17e-33: 113: 64.41		VPP1_MOUSE (1-826): 0: 1287: 46.86
+	Mm
		1376699 VATG2_MOUSE (1-117): 3.14e-30: 106: 95.73		VPP1_MOUSE (1-826): 0: 1287: 46.86
+	Hs
		260090 VATG1_HUMAN (1-118): 1.67e-31: 109: 63.56		VPP1_HUMAN (1-826): 0: 1272: 47.61
+	Hs
		318296 VATG2_HUMAN (1-118): 1.31e-30: 107: 100.00		VPP1_HUMAN (1-826): 0: 1272: 47.61
+	Hs
		318304 VATG2_HUMAN (1-118): 1.31e-30: 107: 100.00		VPP2_HUMAN (1-829): 0: 1181: 50.00
+	Sc
		693224 VATG_YEAST (3-113): 3.05e-23: 88.3: 32.43		VPP1_YEAST (3-829): 0: 1019: 35.82
+	Sc
		741308 VATG_YEAST (3-113): 3.05e-23: 88.3: 32.43		VPP2_YEAST (3-828): 0: 902: 32.13