HitPredict

Interactor 1: BRD1 (O95696)
Bromodomain-containing protein 1 (BR140-like protein) (Bromodomain and PHD finger-containing protein 2)
Gene: BRD1

Interactor 2: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	25281560, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1058 Hs			1 126
+	Hs
		319121 BRD1_HUMAN (1-1058): 0: 1027: 100.00		H2B1O_HUMAN (1-126): 2.88e-54: 167: 98.41
+	Hs
		319214 BRD1_HUMAN (1-1058): 0: 1027: 100.00		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		617938 BRPF1_HUMAN (2-1058): 0: 834: 50.04		H2B1O_HUMAN (1-126): 2.88e-54: 167: 98.41
+	Hs
		876685 BRPF1_HUMAN (2-1058): 0: 834: 50.04		H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00
+	Hs
		876694 BRPF1_HUMAN (2-1058): 0: 834: 50.04		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		617953 JADE1_HUMAN (110-894): 5.55e-121: 393: 22.78		H2B1O_HUMAN (1-126): 2.88e-54: 167: 98.41
+	Hs
		1087195 JADE1_HUMAN (110-894): 5.55e-121: 393: 22.78		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Sc
		356046 NTO1_YEAST (58-613): 9.77e-113: 368: 25.47		H2B2_YEAST (3-125): 5.51e-37: 124: 71.55
+	Sc
		355691 NTO1_YEAST (58-613): 9.77e-113: 368: 25.47		H2B1_YEAST (3-125): 1.92e-36: 122: 71.55
+	Hs
		617963 JADE3_HUMAN (110-590): 6.17e-90: 308: 29.03		H2B1O_HUMAN (1-126): 2.88e-54: 167: 98.41
+	Hs
		1087304 JADE3_HUMAN (110-590): 6.17e-90: 308: 29.03		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		918569 JADE3_HUMAN (110-590): 6.17e-90: 308: 29.03		H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00
+	Hs
		617982 JADE2_HUMAN (110-875): 6.63e-87: 299: 23.23		H2B1O_HUMAN (1-126): 2.88e-54: 167: 98.41
+	Hs
		876570 AF10_HUMAN (217-932): 1.05e-72: 263: 18.87		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		617986 BRPF3_HUMAN (667-1055): 2.04e-69: 255: 34.78		H2B1O_HUMAN (1-126): 2.88e-54: 167: 98.41
+	Hs
		1087475 BRPF3_HUMAN (667-1055): 2.04e-69: 255: 34.78		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		1087293 PHIP_HUMAN (348-939): 3.6e-54: 209: 13.41		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		918554 PHIP_HUMAN (348-939): 3.6e-54: 209: 13.41		H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00
+	Hs
		299044 PHF14_HUMAN (173-572): 2.71e-54: 207: 17.83		H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00
+	Hs
		299040 PHF14_HUMAN (173-572): 2.71e-54: 207: 17.83		H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62