HitPredict

Interactor 1: BRD1 (O95696)
Bromodomain-containing protein 1 (BR140-like protein) (Bromodomain and PHD finger-containing protein 2)
Gene: BRD1

Interactor 2: JADE3 (Q92613)
Protein Jade-3 (Jade family PHD finger protein 3) (PHD finger protein 16)
Gene: JADE3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PHD_2~zf-HC5HC2H_2, zf-HC5HC2H_2~zf-HC5HC2H_2
Common GO terms	GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0046872 - metal ion binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1058 Hs			1 823
+	Hs
		319230 BRD1_HUMAN (1-1058): 0: 1027: 100.00		JADE1_HUMAN (1-798): 0: 677: 43.85
+	Hs
		876709 BRPF1_HUMAN (2-1058): 0: 834: 50.04		JADE3_HUMAN (1-823): 0: 829: 100.00
+	Hs
		319344 BRD1_HUMAN (1-1058): 0: 1027: 100.00		JADE2_HUMAN (2-788): 0: 634: 39.93
+	Hs
		876697 BRPF1_HUMAN (2-1058): 0: 834: 50.04		JADE1_HUMAN (1-798): 0: 677: 43.85
+	Hs
		876722 BRPF1_HUMAN (2-1058): 0: 834: 50.04		JADE2_HUMAN (2-788): 0: 634: 39.93
+	Hs
		319154 BRD1_HUMAN (1-1058): 0: 1027: 100.00		BRPF1_HUMAN (88-783): 7.67e-120: 392: 21.87
+	Hs
		319375 BRD1_HUMAN (1-1058): 0: 1027: 100.00		BRPF3_HUMAN (89-580): 3.44e-116: 382: 26.56
+	Hs
		1152685 JADE1_HUMAN (110-894): 5.55e-121: 393: 22.78		JADE3_HUMAN (1-823): 0: 829: 100.00
+	Hs
		876725 BRPF1_HUMAN (2-1058): 0: 834: 50.04		BRPF3_HUMAN (89-580): 3.44e-116: 382: 26.56
+	Hs
		1152693 JADE1_HUMAN (110-894): 5.55e-121: 393: 22.78		JADE2_HUMAN (2-788): 0: 634: 39.93
+	Hs
		1268052 JADE3_HUMAN (110-590): 6.17e-90: 308: 29.03		JADE2_HUMAN (2-788): 0: 634: 39.93
+	Hs
		1152695 JADE1_HUMAN (110-894): 5.55e-121: 393: 22.78		BRPF3_HUMAN (89-580): 3.44e-116: 382: 26.56
+	Hs
		1268056 JADE3_HUMAN (110-590): 6.17e-90: 308: 29.03		BRPF3_HUMAN (89-580): 3.44e-116: 382: 26.56