HitPredict

Interactor 1: BRD1 (O95696)
Bromodomain-containing protein 1 (BR140-like protein) (Bromodomain and PHD finger-containing protein 2)
Gene: BRD1

Interactor 2: KAT5 (Q92993)
Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) (cPLA(2)-interacting protein)
Gene: KAT5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	31753913, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EPL1~MOZ_SAS, EPL1~zf-MYST
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1058 Hs			1 513
+	Hs
		309639 BRD1_HUMAN (1-1058): 0: 1027: 100.00		KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30
+	Hs
		319291 BRD1_HUMAN (1-1058): 0: 1027: 100.00		KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23
+	Hs
		319284 BRD1_HUMAN (1-1058): 0: 1027: 100.00		KAT6B_HUMAN (144-504): 8.76e-137: 438: 40.65
+	Hs
		309682 BRPF1_HUMAN (2-1058): 0: 834: 50.04		KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30
+	Hs
		876711 BRPF1_HUMAN (2-1058): 0: 834: 50.04		KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23
+	Hs
		876707 BRPF1_HUMAN (2-1058): 0: 834: 50.04		KAT6B_HUMAN (144-504): 8.76e-137: 438: 40.65
+	Hs
		1152687 JADE1_HUMAN (110-894): 5.55e-121: 393: 22.78		KAT5_HUMAN (1-513): 0: 852: 100.00
+	Hs
		309709 JADE1_HUMAN (110-894): 5.55e-121: 393: 22.78		KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30
+	Hs
		1152686 JADE1_HUMAN (110-894): 5.55e-121: 393: 22.78		KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23
+	Hs
		1152682 JADE1_HUMAN (110-894): 5.55e-121: 393: 22.78		KAT6B_HUMAN (144-504): 8.76e-137: 438: 40.65
+	Sp
		251822 NTO1_SCHPO (11-801): 1.51e-127: 408: 23.99		MST2_SCHPO (227-504): 2.16e-139: 409: 50.89
+	Hs
		309723 JADE3_HUMAN (110-590): 6.17e-90: 308: 29.03		KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30
+	Hs
		309750 JADE2_HUMAN (110-875): 6.63e-87: 299: 23.23		KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30
+	Hs
		1268046 JADE3_HUMAN (110-590): 6.17e-90: 308: 29.03		KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23
+	Sc
		710457 NTO1_YEAST (58-613): 9.77e-113: 368: 25.47		SAS3_YEAST (208-504): 1.23e-123: 382: 40.66
+	Hs
		1264456 JADE3_HUMAN (110-590): 6.17e-90: 308: 29.03		KAT6B_HUMAN (144-504): 8.76e-137: 438: 40.65
+	Hs
		1270944 JADE2_HUMAN (110-875): 6.63e-87: 299: 23.23		KAT6A_HUMAN (70-504): 1.5e-138: 442: 37.23
+	Hs
		1264462 JADE2_HUMAN (110-875): 6.63e-87: 299: 23.23		KAT6B_HUMAN (144-504): 8.76e-137: 438: 40.65
+	Hs
		309758 BRPF3_HUMAN (667-1055): 2.04e-69: 255: 34.78		KAT7_HUMAN (111-504): 1.86e-157: 463: 40.30
+	Hs
		1264463 BRPF3_HUMAN (667-1055): 2.04e-69: 255: 34.78		KAT6B_HUMAN (144-504): 8.76e-137: 438: 40.65